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1.
Jurnal Pengukuran Psikologi dan Pendidikan Indonesia ; 12(1):17-30, 2023.
Article in English | Scopus | ID: covidwho-20239615

ABSTRACT

Research that examines the construct validity of Posttraumatic Growth Inventory in the context of the COVID-19 pandemic has never been conducted. This study aimed to test the construct validity of Posttraumatic Growth Inventory (PTGI) on the five dimensions to see the consistency of the PTGI dimensionality structure. Data collection was carried out on 135 COVID-19 survivors, aged 18–40 in Indonesia. Analysis was carried out by confirmatory factor analysis (CFA) and measurement invariance (MI). The results of the analysis proved that PTGI is a measuring instrument that tends to be multidimensional and reliable to be used in Indonesia. All model fit indices met the parameters based on the values of SRMR (<.06), RMSEA (<.10), CFI (>.85), and TLI (>.85). Factor loadings ranged from 0.616 to 0.839 except for item 6 and item 9, which were below 0.6. These low loading factors in item 6 and item 9 were caused by the choice of translated words which tend to be less precise with the dimension being measured. Recommendations related to changes in translated words were explained further in the article as a follow-up to the adjustment of the item statement. Other factors such as personality characteristics, level of self-esteem, and social stigma were also found to be associated with the results of the analysis. MI testing showed that the PTGI model was not influenced by gender in the study sample group. © 2023, Syarif Hidayatullah State Islamic University (UIN) Jakarta. All rights reserved.

2.
Family & Consumer Sciences Research Journal ; 2023.
Article in English | Web of Science | ID: covidwho-20231104

ABSTRACT

The recent COVID-19 pandemic experience intensified the significance of hygiene in the service industry. It is crucial to measure how service practice adaptations and technology adoptions in servicescapes have been perceived by customers regarding hygiene in the post-COVID-19 era. However, the extant hygiene scales do not serve the purpose to measure hygiene contributions of technology-specific and service practice-specific changes. Thus, the purpose of this research was to develop a multi-item unidimensional perceived hygiene construct. Sequential mixed-methods research (Qual-Quan) was employed. Participants were sampled among restaurant patrons. A four-item perceived hygiene development (pHd) construct was successfully developed. Hospitality and service researchers and practitioners can utilize this scale to measure perceived hygiene improvements of particular technology adoptions and service practice adaptations in service settings.

3.
Journal of Personnel Psychology ; 2023.
Article in English | Web of Science | ID: covidwho-20231018

ABSTRACT

The early stages of the COVID-19 pandemic were a time of great job insecurity. Knowledge of how such feelings of insecurity were mitigated during a time of crisis has important implications for the development of future interventions. Drawing from uncertainty management theory (UMT), we explored the impact of informational justice perceptions on the effects of job insecurity in a sample collected during the early stages of the pandemic (March-May 2020). The findings indicated that informational justice buffered the impacts of job insecurity on employee life satisfaction and perceived ability to perform. Furthermore, the source of information regarding COVID-19-related job changes mattered for predicting informational justice perceptions. Our findings bolster UMT and have important practical implications for future times of crisis.

4.
Critical Care Conference: 42nd International Symposium on Intensive Care and Emergency Medicine Brussels Belgium ; 27(Supplement 1), 2023.
Article in English | EMBASE | ID: covidwho-2318614

ABSTRACT

Introduction: Indicators that assess relationships among leukocytes may inform more and/or earlier than those measured in isolation. Method(s): Blood leukocyte differential counts collected from 101 Mayo Clinic COVID-19 patients were related to later outcomes following two approaches: (i) as unstructured data (e.g., lymphocyte percentages) and (ii) as data structures that assess intercellular interactions. Analyzing the same primary data, it was asked whether information contents differed among methods and/or when two sets of structured indicators are used. Result(s): While unstructured data did not distinguish survivors from non-survivors (Fig. 1, rectangle A), one data structure (here identified with letters expressed in italics) exhibited one perpendicular inflection that differentiated two patient groups (B). Two survivor-related observations were also distinguished from the remaining data points (B). A second data structure also revealed a single line of observations and a perpendicular data inflection (C), while more (four) patient groups were identified (D). Four validations were conducted: (i) increasing mortality levels among contiguous data subsets (0, 7.1, 16.2, or 44.4%) suggested construct validity (D);(ii) internal validity was indicated because 22 of the 45 survivors detected by the first data structure were also captured by the second one;(iii) the analysis of patients that differed in address, co-morbidities and other aspects supported external validity;and (iv) quasi non-overlapping data intervals predicted statistical validity (E, F). The structured approach also uncovered new and/ or dissimilar information: different leukocyte-related ratios explained the clusters identified in these analyses (E, F). Conclusion(s): Structured data may yield more information than methods that do not assess multicellular interactions. Possible applications include daily, longitudinal, and personalized analysis of hospital data.

5.
Appl Res Qual Life ; : 1-24, 2022 Nov 03.
Article in English | MEDLINE | ID: covidwho-2314848

ABSTRACT

Studies on the prevalence of burnout in professionals in service organizations who work in direct contact with the clients or users of the organization have concluded that burnout is a serious health disorder that has increased due to the COVID-19 pandemic. A significant advantage of the Spanish Burnout Inventory (SBI) over other instruments is that it provides a broader conceptualization of burnout by including feelings of guilt as a dimension of burnout to explain its development. However, the measurement invariance of the SBI across countries has not been investigated. The purpose of this study was to test the measurement invariance of the SBI among professionals across 17 countries and regions in Europe, Latin America, and Asia, and in different languages. All the countries showed a good fit to the four-factor model, except the Indian sample, which was excluded from the measurement invariance study. Using the alignment method, it was possible to verify the scalar measurement invariance of the four SBI factors across 15 countries and one Spanish region (16 samples). The comparison of estimated latent means indicates that France is the country with the lowest scores on the Enthusiasm factor and the highest scores on the negative factors (Exhaustion, Indolence, and Guilt). In contrast, the Andean countries, Colombia, Peru, and Ecuador, show the highest latent means on the Enthusiasm factor and the lowest means on the negative factors. These results support the validity of the SBI in the countries and regions in Europe and Latin America included in this study.

6.
Psychology-Journal of the Higher School of Economics ; 19(3):454-474, 2022.
Article in English | Web of Science | ID: covidwho-2309778

ABSTRACT

The paper presents the results of the study on development and standardization of the "COVID-19 Vaccine Attitude Scale" (COVID- 19 VAS) questionnaire. The study sample includes N = 1965 undergraduate, specialist and master students, of which N = 1592 (81%) are women and N = 373 (19%) are men aged 16 to 60 years, mean age M = 24.7, SD = 8.4, Me = 21.0. Study was conducted at Moscow State University of Psychology & Education (MSUPE). The questionnaire structure includes 5 scales identified by the method of exploratory factor analysis: Scale 1 "The benefits of vaccination against COVID-19 for an individual and society", Scale 2 "Fear of incidental effects of vaccination against COVID-19 and distrust of information about the vaccination safety", Scale 3 "Denial of the danger of coronavirus and hope for natural immunity", Scale 4 "Confidence in the serious negative consequences of the coronavirus vaccine" and Scale 5 "Disbelief in the proven international level effectiveness of Russian vaccines". The construct validity of the questionnaire was statistically proved. Confirmatory factor analysis verified satisfactory goodness-of-fit between the empirical data and the questionnaire structure. The scales are moderately intercorrelated, and the directions of the correlations correspond to the expected ones. The high internal reliability of all scales is statistically confirmed with the Cronbach's alpha coefficient. Satisfactory convergent validity of the corresponding scales of the "COVID-19 Vaccine Attitude Scale (COVID-19 VAS)" with natural science literacy, intelligence and fear of COVID-19 disease is also confirmed. All correlations are weak, but theoretically expected and explainable. The differential validity is statistically proved. Stanines are calculated. The COVID-19 VAS can be recommended for preparation, realization and evaluation of the effectiveness of educational activities on vaccine prevention against COVID-19 among university students.

7.
Journal of Cardiac Failure ; 29(4):566, 2023.
Article in English | EMBASE | ID: covidwho-2302544

ABSTRACT

Behavioral benefits of the COVID lockdown have been suggested for patients with heart failure (HF) but little is known about the effects of the pandemic on the family and loved ones who care for these patients. The purpose of this study was to compare self-reported self-care neglect among HF caregivers in the months preceding the pandemic (August 2019 through March 2020) to the self-care neglect reported by HF caregivers in the early months of the pandemic (May 2020 through December 2020). Method(s): Baseline data from an ongoing study with HF caregivers were used for this analysis. All potentially eligible caregivers are screened for self-care neglect;those who score >=2 on the 10-item Health Self-Care Neglect scale (construct validity, alpha reliability.90) are eligible for study enrollment. Possible scores range from 0-10;lower is better. Baseline data before randomization were used for this analysis. Before the pandemic, 40 caregivers were enrolled. In the early months after the pandemic began, we enrolled another 55 caregivers. Participants' demographic and clinical characteristics were compared between groups. Regression analysis was used to identify group differences in self-care neglect, adjusting for group differences at baseline. Result(s): The sample of 95 HF caregivers was predominately White (64%), female (89.5%), spouses (66%), age 54.7 +/- 13.5 years, and caregiving 9.2 +/- 8 hours/day. Only sex differed significantly between the groups;pre-pandemic the sample was 97.5% female but during the early months of the pandemic it was 83.6% female. Health Self-Care Neglect scores were higher (worse) pre-pandemic compared to the early months of the pandemic after accounting for sex (5.3 +/- 0.5 vs. 4.3 +/- 0.4, p=0.04). When individual items on the scale were analyzed, only the proportion of caregivers who put off going to the doctor significantly differed between pre-pandemic (62.5%) and early-pandemic (40%, p=0.03) groups. Conclusion(s): Health Self-care Neglect was higher in HF caregivers before the pandemic began. It may be that the pandemic encouraged caregivers to focus on their health.Copyright © 2022

8.
Psychology, Journal of the Higher School of Economics ; 19(3):454-474, 2022.
Article in Russian | Scopus | ID: covidwho-2270842

ABSTRACT

The paper presents the results of the study on development and standardization of the "COVID-19 Vaccine Attitude Scale” (COVID-19 VAS) questionnaire. The study sample includes N = 1965 undergraduate, specialist and master students, of which N = 1592 (81%) are women and N = 373 (19%) are men aged 16 to 60 years, mean age M = 24.7, SD = 8.4, Me = 21.0. Study was conducted at Moscow State University of Psychology & Education (MSUPE). The questionnaire structure includes 5 scales identified by the method of exploratory factor analysis: Scale 1 "The benefits of vaccination against COVID-19 for an individual and society", Scale 2 "Fear of incidental effects of vaccination against COVID-19 and distrust of information about the vaccination safety", Scale 3 "Denial of the danger of coronavirus and hope for natural immunity”, Scale 4 "Confidence in the serious negative consequences of the coronavirus vaccine” and Scale 5 "Disbelief in the proven international level effectiveness of Russian vaccines”. The construct validity of the questionnaire was statistically proved. Confirmatory factor analysis verified satisfactory goodness-of-fit between the empirical data and the questionnaire structure. The scales are moderately intercorrelated, and the directions of the correlations correspond to the expected ones. The high internal reliability of all scales is statistically confirmed with the Cronbach's alpha coefficient. Satisfactory convergent validity of the corresponding scales of the "COVID-19 Vaccine Attitude Scale (COVID-19 VAS)” with natural science literacy, intelligence and fear of COVID-19 disease is also confirmed. All correlations are weak, but theoretically expected and explainable. The differential validity is statistically proved. Stanines are calculated. The COVID-19 VAS can be recommended for preparation, realization and evaluation of the effectiveness of educational activities on vaccine prevention against COVID-19 among university students. © 2022 National Research University Higher School of Economics. All rights reserved.

9.
17th Latin American Conference on Learning Technologies, LACLO 2022 ; 2022.
Article in Spanish | Scopus | ID: covidwho-2254462

ABSTRACT

To obtain useful, valid, and reliable results, it is essential to carry out a cross-cultural adaptation process when using measurement instruments developed in other cultures, contexts, and populations with a different language from the original one. An instrumental study was conducted to determine the validity and reliability of the 'Students' knowledge and use of digital technology during the COVID-19 pandemic' questionnaire, developed in another context and different culture from the original one. The participants were 139 students of the Communications program of a private higher education institute in Lima, selected by non-probabilistic convenience sampling. The study presents a proposal consisting of eight factors and 56 items, as opposed to the original structure composed of seven factors and 77 items. The analyses show that the instrument is valid and reliable among the population under study. © 2022 IEEE.

10.
Analyses of Social Issues and Public Policy (ASAP) ; 21(1):557-578, 2021.
Article in English | APA PsycInfo | ID: covidwho-2281491

ABSTRACT

Developing psychometrically validated assessment tools to examine social and intergroup processes related to COVID-19 is fundamental for creating interventions that reduce the spread of this virus. Thus, this manuscript aimed to evaluate the psychometric properties of a new measure, Assessment of COVID-19 Attitudes and Behaviors (ACAB), that assesses COVID-19-related attitudes (e.g., about physical distancing, xenophobia), behaviors (e.g., helping others versus prioritizing own needs), and beliefs (e.g., about others' roles in spreading COVID-19). We used exploratory and confirmatory factor analyses (EFA, CFA) to provide factor analytic support and Fisher's r-to-z transformation to provide construct validity evidence. EFA revealed and CFA confirmed a four-factor structure of social distancing adjustment, self-prioritization, prosocial behaviors, and belief in conspiracies. Fisher's r-to-z transformation provided evidence for the construct validity of the four factors. This psychometrically validated instrument will enhance social science researchers' ability to accurately identify and explicate psychological processes related to COVID-19. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

11.
International Journal of Human Rights in Healthcare ; 15(3):257-275, 2022.
Article in English | APA PsycInfo | ID: covidwho-2280780

ABSTRACT

Purpose: Ostracism is being socially ignored or excluded by others. Ostracism leads to serious psychological distress and health issues in the young adults being ostracized. However, there are no psychometrically designed instruments to measure this phenomenon in young adults. This study aims to develop a scale that measures ostracism efficiently and establishes the scale's psychometric properties. Design/methodology/approach: The research design used for the study is "a mixed-method study using non-experimental research with an exploratory sequential approach and instrument development design." For the formation of the item pool, theoretical evidence was collected and focus group discussions were conducted. Afterward, content validity was established with the help of subject matter experts, followed by Velicer's minimum average partial method and maximum likelihood factor analysis to form the instrument's factorial structure. Findings: Velicer's minimum average partial method and maximum likelihood factor analysis made two factors as follows: ostracism experience and psychological effect. The instrument developed has a high value of alpha reliability i.e. a = 0.97 and a = 0.96, a = 0.92 for the subscales, respectively. Research limitations/implications: The sample used for the research was enough to run the analysis, but future studies can go for a more extensive and more diverse sample. The sample was based solely on university students. The current research focused only on the target of the phenomenon, and the whole research process was conducted online because of the Covid-19 pandemic going on. The scale developed can be used in several settings to find out if the individual is being ostracized or not. Practical implications: The scale's most important implication is in the colleges and universities where young adults are found and face this problem daily. Likewise, psychologists can also use it in clinical settings. The other important implication of this scale is that it is opening a route to future research as different variables can be studied in ostracism such as depression, physical health and anxiety. Social implications: Ostracism is a hidden evil in societies that is not usually talked about. When people are not given equal importance in groups or settings, it leads to serious psychological issues in those individuals. This scale will in the identification of the problem that will lead to a proper solution to this evil. Originality/value: This work is original and not copied from anywhere. The research was conducted with the sole purpose of developing a scale on the ostracism experiences in young adults. The data is collected in the form of online surveys. The current scale is an attempt at developing a more reliable and valid scale that can be used in social settings. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

12.
J Health Psychol ; : 13591053221106129, 2022 Jul 05.
Article in English | MEDLINE | ID: covidwho-2280219

ABSTRACT

The Pandemic Anxiety Inventory (PAI) assesses anxiety symptoms individuals attribute to the presence of a pandemic. We conducted this study of 379 British adults during the COVID-19 pandemic and found that the PAI exhibited excellent reliability and solid criterion validity. Pandemic anxiety was associated with reduced social support, anticipated life changes, financial strain, job loss, economic insecurity, and the hospitalization or death of a close friend or relative. Using correlational and bifactor analyses, we found that the PAI demonstrated solid convergent and discriminant validity. The findings suggest that the PAI can be used in research and clinical practice.

13.
Journal of Constructivist Psychology ; 36(1):22-44, 2023.
Article in English | Scopus | ID: covidwho-2246118

ABSTRACT

The COVID-19 pandemic could be considered as a career shock for employees in different industries around the world. The aim of this research was to gain insight into the dynamics of Serbian small business owners' career shocks caused by the COVID-19 pandemic by using personal construct psychology (PCP) as a theoretical framework. We conducted 18 semi-structured interviews with 9 small business owners on two separate occasions and analyzed their personal stories. The data were collected during the most restrictive lockdown in Serbia in April 2020 and again at the end of June 2020 when the number of the people infected was on a rapid rise. The reaction to the career shock caused by the pandemic can be understood by analyzing transitions (how people perceive career shocks), people's coping strategies and the way in which their dependencies were dispersed. This study contributes to understanding the career shock issue by viewing it through the lens of the personal construct theory. © 2021 Taylor & Francis Group, LLC.

14.
Journal of Adolescent Research ; 2023.
Article in English | Web of Science | ID: covidwho-2244134

ABSTRACT

There is emerging evidence of the detrimental impact of the pandemic and associated restrictions on young people's mental health in the UK but to date, these data have been largely quantitative. The aim of the current study was to gain a deeper understanding of young people's experiences in relation to their mental health and wellbeing during the pandemic. Seventeen young people, aged 11 to 16 years, sampled for diverse characteristics, and living in the UK, were interviewed virtually between December 2020 and February 2021. Reflexive thematic analysis was carried out by the research team, which included two young people, and five themes were developed: (1) positives;(2) worries and anxiety;(3) sadness and anger about losses;(4) mental exhaustion;and (5) support from others. Aspects of young people's individual circumstances (e.g., pre-existing mental health difficulties;special educational needs and neurodevelopmental disorders) appeared to play a role in their experiences. Continued measurement of young people's mental health, initiatives to identify young people who have been struggling and the provision of support (including evidence-based and accessible interventions) will be important for protecting young people from future adversities as we emerge from the pandemic.

15.
Psychology-Journal of the Higher School of Economics ; 19(3):454-474, 2022.
Article in Russian | Web of Science | ID: covidwho-2243104

ABSTRACT

The paper presents the results of the study on development and standardization of the "COVID-19 Vaccine Attitude Scale" (COVID- 19 VAS) questionnaire. The study sample includes N = 1965 undergraduate, specialist and master students, of which N = 1592 (81%) are women and N = 373 (19%) are men aged 16 to 60 years, mean age M = 24.7, SD = 8.4, Me = 21.0. Study was conducted at Moscow State University of Psychology & Education (MSUPE). The questionnaire structure includes 5 scales identified by the method of exploratory factor analysis: Scale 1 "The benefits of vaccination against COVID-19 for an individual and society", Scale 2 "Fear of incidental effects of vaccination against COVID-19 and distrust of information about the vaccination safety", Scale 3 "Denial of the danger of coronavirus and hope for natural immunity", Scale 4 "Confidence in the serious negative consequences of the coronavirus vaccine" and Scale 5 "Disbelief in the proven international level effectiveness of Russian vaccines". The construct validity of the questionnaire was statistically proved. Confirmatory factor analysis verified satisfactory goodness-of-fit between the empirical data and the questionnaire structure. The scales are moderately intercorrelated, and the directions of the correlations correspond to the expected ones. The high internal reliability of all scales is statistically confirmed with the Cronbach's alpha coefficient. Satisfactory convergent validity of the corresponding scales of the "COVID-19 Vaccine Attitude Scale (COVID-19 VAS)" with natural science literacy, intelligence and fear of COVID-19 disease is also confirmed. All correlations are weak, but theoretically expected and explainable. The differential validity is statistically proved. Stanines are calculated. The COVID-19 VAS can be recommended for preparation, realization and evaluation of the effectiveness of educational activities on vaccine prevention against COVID-19 among university students.

16.
International Journal of Teacher Leadership ; 11(1):5-28, 2022.
Article in English | ProQuest Central | ID: covidwho-2057945

ABSTRACT

When teachers have a practical, easy to use tool to self-assess acts of teacher leadership, they are better equipped to develop as leaders by self-determining to whom or what they are committed (relatedness), what they know and can do (competence), and when and how to act (autonomy). The purpose of this mixed methods study was to assess the validity of the Five Features of Teacher Leadership Framework and Self-Determination Guide (FFTL) through field testing by credentialed teacher leaders. Twenty-five credentialed teacher leaders representing all six regions of the United States participated in the study. The FFTL was favorably viewed by all 25 teacher leaders, revealing reasonably strong confidence in the tool's face, content, and construct validity. The findings suggest that participants considered the FFTL credible enough to trust as a guide for self-determining acts of teacher leadership. By describing an act of teacher leadership and using the FFTL to self-determine the degree to which the act accomplished the five core features of teacher leadership, the teacher leaders in this study were empowered to grow and develop as leaders privately, in their own way, and at their own pace. More research is needed.

17.
International Journal of Emerging Markets ; 2022.
Article in English | Web of Science | ID: covidwho-2191434

ABSTRACT

PurposeThe study aims to identify the extent to which industry 4.0 (IR4.0) adoption impacts the sustainable manufacturing (SM) performance of the manufacturing industry, focusing on the comparative analysis between developed and developing economies amid coronavirus disease 2019 (COVID-19) pandemic.Design/methodology/approachThe study proposes a conceptual model formed on seminal theories and literature using the cross-sectional design. For data collection, a purposive sampling method is used where 154 Malaysian (developing) and Australian (developed) manufacturing firms' data were collected. Partial least square-based structural equation modeling is employed to test the hypothesis and proposed research model.FindingsThis study finds that adoption of IR4.0 technologies does not directly influence the sustainability performance of the manufacturing industry, but rather the trajectories of SM (efficiency, flexibility, automation and big data and granularity) fully mediate the relationship between IR4.0 adoption and sustainability manufacturing performance. The comparative analysis between Australia and Malaysia shows no significant difference in the relationships or the framework;hence, the differences between developed and developing countries are not significant in this mechanism.Originality/valueThe study contributes to the insights of the managers regarding COVID-19 and the implementation of IR4.0 in the SM domain. The policymakers would further get better insights since the study pays attention to sustainable development goal, industry, innovation, infrastructure and responsible production.

18.
IOP Conference Series. Earth and Environmental Science ; 1115(1):012005, 2022.
Article in English | ProQuest Central | ID: covidwho-2160872

ABSTRACT

Theory of Planned Behavior (TPB) has been implemented to evaluate the structure of behavioral change of the local communities in the forest and wildlife conservation program in Tangkahan, the eastern part of GLNP. This study has the purpose to reveal the determinant factors of local community behavior to support forest and wildlife conservation through ecotourism activities and to formulate a strategy to recover wildlife ecotourism in the post-COVID-19 outbreak. The study was conducted in Tangkahan through a survey method to collect the data. The data were analyzed using linear regression analysis. This study found that the determinant factors of behavioral intention are the conservation attitude and perceived behavioral control and behavioral intention significantly affects the behavior to participate in conservation activities. To improve the visiting number and the ecotourism service in Tangkahan in the post-COVID 19 outbreak, the community should transform and develop the management system from a conventional to virtual/digital method, develop and follow the COVID-19 protocol of ecotourism, re-arrange the ticket fee and the tour packages to cope with domestic visitors and improve the access to the area by constructing the roads and provision of transportation services.

19.
Sains Malaysiana ; 51(9):2985-2997, 2022.
Article in English | Scopus | ID: covidwho-2145716

ABSTRACT

COVID-19 caused by the SARS-CoV-2 virus has become a real threat due to the emergence of new variants which are more deadly with higher infectivity. Vaccine constructs that target specific SARS-CoV-2 variants are needed for stemming COVID-19 fatality. The spike (S) glycoprotein is the major antigenic component that triggers the host immune response. Reverse vaccinology strategy was applied to the S protein of COVID-19 variant D614G to identify highly ranked antigenic proteins. In this study, a multi-epitope synthetic gene was designed using computational strategies for the COVID-19 D614G variant. The SARS-CoV-2 D614G variant protein sequence was retrieved from the NCBI database. The prediction of linear B-cell epitopes was carried out using Artificial Neural Network (ANN)-based ABCpred and BepiPred 2.0 software. The top 15 highly antigenic epitopes sequences were then selected. Propred 1 and Propred servers were used to identify major histocompatibility complex (MHC) class I and class II binding epitopes within pre-determined B-cell epitopes to predict T-cell epitopes. The top 5 MHC class I and class II were selected. Further in-silico testing for its solubility, allergenicity, antigenicity, and other physiochemical properties was analyzed using Bpred. The constructed gene was subjected to assembly PCR and the gene product was confirmed by Sanger sequencing. The findings from this study suggested that a highly antigenic specific region of the SARS-CoV-2 D614G variant can be predicted in-silico and amplified using the assembly PCR method. The designed synthetic gene was shown to elicit specific humoral and cell-mediated immune responses towards the SARS-CoV-2 variants. © 2022 Penerbit Universiti Kebangsaan Malaysia. All rights reserved.

20.
24th International Electronics Symposium, IES 2022 ; : 638-643, 2022.
Article in English | Scopus | ID: covidwho-2078223

ABSTRACT

A learning process that always relies on books makes students less interesting and less motivating in learning. Because of the Covid-19 pandemic, the learning utilizes learning applications and social media such as short message applications. This has a bad impact because it can affect the mentality of the learning process [1], so it is necessary to make adjustments for improvements in the development of a more enjoyable learning process, one of which is by using game applications. It needs an improvement in the development of a more fun learning process, one of which is by using game applications. Game development in learning has not been too focused on the world of education, even though currently many games can be a good learning medium. This research develops a learning media gamification method with speech commands support features contained in Construct 3. This application can be used with mouse clicks or speech commands. The use of gamification with game elements outside of game contests has proven to be effective in increasing students' motivation and interest in learning. © 2022 IEEE.

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